Tsu-Ming Han left China and came to the United States in 1948, when he was twenty-two years old. He received his bachelor’s degree in geology from the National Northwestern University of Si-An, China, his master’s degree from the University of Cincinnati, and a Ph.D. in economic geology from the University of Minnesota. He began working as a mineralogist for the Geological and Metallurgical Departments at the Cleveland-Cliffs Research Laboratory in 1953. In 1967, he was promoted to the position of Senior Research Scientist in the Mineralogical Section at the Research Laboratory. In the fall of 1990, Tsu-Ming Han discovered a fossil in a light-colored area of the eastern wall of the Empire Mine. The fossil was determined to be 2.1 billion years old and was identified as Grypania spiralis.
Tsu-Ming Han was a member of the Society of Economic Geologists, the Mineralogical Association of Canada, the Mineralogical Society of America, the Society for Applied Geology of Mineral Deposits, Xigma Xi, and the Scientific Research Society of America. Tsu-Ming Han, his wife Joy, and children, Lisa, Dennis, and Timothy, lived in Ishpeming, Michigan, and were members of Bethany Lutheran Church of Ishpeming.